Shows Like Opposite Sex
If you enjoyed Opposite Sex, you will appreciate how these films questions the purpose and weight of our choices while maintaining targets the intellect with complex, multi-layered ideas. Carefully balances character depth with narrative flow makes this a solid addition to your watchlist.
Standard feature-length experiences.
Best for fans of who appreciate concise storytelling.
★ Top Picks

My Three Sons
A widower and aeronautical engineer named Steven Douglas raises three sons with the help of his father-in-law, and later the boys' great-uncle. An adopted son, a stepdaughter, wives, and another generation of sons join the loving family in later seasons.

Blossom
Blossom Russo is a highly intelligent and spunky teenager. The youngest of three, she lives with her divorced musician father, Nick, eldest brother and recovering substance abuser Anthony, and decidedly not-so-bright middle brother Joey. Along for the ride is Blossom's ditzy best friend, Six, who sometimes shows flashes of great perception.

Marlon
A loving (but immature) father is committed to co-parenting his two kids with his very-together ex-wife. While his misguided fatherly advice, unstoppable larger-than-life personality and unpredictable Internet superstardom might get in the way sometimes, for Marlon, family really always does come first - even if he's the biggest kid of all.

The Game
When her boyfriend Derwin Davis is chosen as the new third-string wide receiver for the San Diego Sabers, Melanie Barnett decides to attend a local college so she can be with him. While Derwin worries about the plays on the field, Melanie adjusts to her new lifestyle. She gets a play-by-play account of the lives and relationships among NFL wives, girlfriends and mom/managers who use their best game to help their men stay on the field and on their arm.

Shameless
Chicagoan Frank Gallagher is the proud single dad of six smart, industrious, independent kids, who without him would be... perhaps better off. When Frank's not at the bar spending what little money they have, he's passed out on the floor. But the kids have found ways to grow up in spite of him. They may not be like any family you know, but they make no apologies for being exactly who they are.

The O.C.
Ryan Atwood, a teen from the wrong side of the tracks, moves in with a wealthy family willing to give him a chance. But Ryan's arrival disturbs the status quo of the affluent, privileged community of Newport Beach, California.

Louie
Louis C.K. stars as a fictionalized version of himself; a comedian and newly divorced father raising his two daughters in New York City.

Suburgatory
Single father George Altman is doing his best to raise his sixteen-year-old daughter Tessa in the big city. When he discovers a box of condoms in her bedroom, though, he decides the time has come to move her to a more wholesome and nurturing environment: the suburbs. But behind the beautiful homes and perfect lawns lurk the Franken-moms, spray tans, nose jobs, and Red Bull-guzzling teens who have nothing in common with Tessa. It’s a whole new world, one that makes George wonder if they haven’t jumped out of the frying pan and into the fire.
More Shows Like Opposite Sex

One Day at a Time
The misadventures of a divorced mother, two teenage daughters, and new building superintendent in Indianapolis.

Flaked
In his funky California beach enclave, Chip's the go-to guy for personal insights. But he isn't quite as enlightened when it comes to his own baggage.

Knots Landing
The domestic adventures, misdeeds and everyday interactions of five families living on a cul-de-sac in a small California community.

Crazy Ex-Girlfriend
Rebecca Bunch is a successful, driven, and possibly crazy young woman who impulsively gives up everything - her partnership at a prestigious law firm and her upscale apartment in Manhattan - in a desperate attempt to find love and happiness in that exotic hotbed of romance and adventure: suburban West Covina, California.

The Millers
A divorced reporter, looking forward to the single life, finds his parents' marital problems derail his plans.

Sister Wives
Husband Kody Brown, along with his four wives (only one of which is legally married to Kody) and their combined 18 children, attempts to navigate life as a "normal" family in a society that shuns their lifestyle.

Looking
Three friends in San Francisco who explore the fun and sometimes overwhelming options available to a new generation of gay men.

Greenleaf
The unscrupulous world of the Greenleaf family and their sprawling Memphis megachurch, where scandalous secrets and lies are as numerous as the faithful. Born of the church, the Greenleaf family love and care for each other, but beneath the surface lies a den of iniquity—greed, adultery, sibling rivalry and conflicting values—that threatens to tear apart the very core of their faith that holds them together.

Speechless
Maya DiMeo is a mom on a mission who will do anything for her husband, Jimmy, and kids Ray, Dylan, and JJ, her eldest son with special needs. As Maya fights injustices both real and imagined, the family works to make a new home for themselves and searches for just the right person to give JJ his “voice.”

Californication
A self-loathing, alcoholic writer attempts to repair his damaged relationships with his daughter and her mother while combating sex addiction, a budding drug problem, and the seeming inability to avoid making bad decisions.

Tyler Perry's The Oval
A seemingly perfect interracial first family becomes the White House's newest residents. But behind closed doors they unleash a torrent of lies, cheating and corruption.

Why These Shows Are Similar
These recommendations share core qualities with Opposite Sex (2000): Drama and Comedy themes, similar pacing, and comparable production quality. NoBadPicks uses TMDB collaborative filtering, genre matching, and AI analysis to surface series most likely to resonate with fans of Opposite Sex.
See full details for Opposite Sex (2000)



